November 23, 2009, Monday
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Biomechanics of Bacteremia

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Bacterial floc
Bacterial floc

Overview

This project focuses on studying how populations of aggregated bacterial communities behave in the bloodstream. This research is part of a longstanding collaboration between an applied mathematician Dr. Bortz and an emergency room physician Dr. Younger. Recently, we have had two papers appear:

H. Chung, M. M. Cartwright, D. M. Bortz, T. L. Jackson, and J. G. Younger, Dynamical System Analysis of Staphylococcus epidermidis Bloodstream Infection, SHOCK, 30(5):518-526, November 2008.

D. M. Bortz, T. L. Jackson, K. A. Taylor, A. P. Thompson, and J. G. Younger, Klebsiella pneumoniae flocculation dynamics, Bulletin of Mathematical Biology, 70(3):745-768, April 2008.


Background

Bacterial pathogens like Klebsiella pnuemoniae and Staphylococcus epidermidis are causes of community- and hospital-acquired blood stream infections, as well as many other common types of infections. Surviving a bloodstream infection requires effective filtration of bacteria from the blood and elimination of pathogens from organs that have been seeded during episodes of bacteremia.

Current Work

coming soon...